Polyester fabric-based nano copper-polyhedral oligomeric silsesquioxanes sorbent for thin film extraction of non-steroidal anti-inflammatory drugs
In this study, in-situ preparation of copper nanoparticles under sonoheating conditions followed by coating on commercial polyester fabric is reported. Through the self-assembly interaction of thiol groups and copper nanoparticles, the modified polyhedral oligomeric silsesquioxanes (POSS) was deposited on the fabric's surface. In the next step, radical thiol-ene click reactions were implemented to create more layers of POSSs. Subsequently, the modified fabric was applied for sorptive thin film extraction of non-steroidal anti-inflammatory drugs (NSAIDs) including naproxen, ibuprofen, diclofenac, and mefenamic acid from uri...
Source: Analytica Chimica Acta - June 13, 2023 Category: Chemistry Authors: Nasrin Moradi Gohar Soufi Abuzar Kabir Majid Karimi Habib Bagheri Source Type: research
Polyester fabric-based nano copper-polyhedral oligomeric silsesquioxanes sorbent for thin film extraction of non-steroidal anti-inflammatory drugs
In this study, in-situ preparation of copper nanoparticles under sonoheating conditions followed by coating on commercial polyester fabric is reported. Through the self-assembly interaction of thiol groups and copper nanoparticles, the modified polyhedral oligomeric silsesquioxanes (POSS) was deposited on the fabric's surface. In the next step, radical thiol-ene click reactions were implemented to create more layers of POSSs. Subsequently, the modified fabric was applied for sorptive thin film extraction of non-steroidal anti-inflammatory drugs (NSAIDs) including naproxen, ibuprofen, diclofenac, and mefenamic acid from uri...
Source: Analytica Chimica Acta - June 13, 2023 Category: Chemistry Authors: Nasrin Moradi Gohar Soufi Abuzar Kabir Majid Karimi Habib Bagheri Source Type: research
Polyester fabric-based nano copper-polyhedral oligomeric silsesquioxanes sorbent for thin film extraction of non-steroidal anti-inflammatory drugs
In this study, in-situ preparation of copper nanoparticles under sonoheating conditions followed by coating on commercial polyester fabric is reported. Through the self-assembly interaction of thiol groups and copper nanoparticles, the modified polyhedral oligomeric silsesquioxanes (POSS) was deposited on the fabric's surface. In the next step, radical thiol-ene click reactions were implemented to create more layers of POSSs. Subsequently, the modified fabric was applied for sorptive thin film extraction of non-steroidal anti-inflammatory drugs (NSAIDs) including naproxen, ibuprofen, diclofenac, and mefenamic acid from uri...
Source: Analytica Chimica Acta - June 13, 2023 Category: Chemistry Authors: Nasrin Moradi Gohar Soufi Abuzar Kabir Majid Karimi Habib Bagheri Source Type: research
Effect of biosolids amendment on the fate and mobility of non-steroidal anti-inflammatory drugs (NSAIDs) in a field-based lysimeter cell study
Environ Pollut. 2023 May 30:121939. doi: 10.1016/j.envpol.2023.121939. Online ahead of print.ABSTRACTNon-steroidal anti-inflammatory drugs (NSAIDs) are widely used globally to treat and prevent illness. Biosolids change physico-chemical characteristics of soil and can affect the mobility of NSAIDs. A field-based lysimeter study evaluated the effect of three rates (0, 7, and 28 Mg ha-1) of alkaline treated biosolids (ATB) on the leaching potential of naproxen (NPX), ibuprofen (IBF), and ketoprofen (KTF) over 34 days in a sandy loam textured soil. Although all three NSAIDs in the lysimeter cells vertically migrated to deeper...
Source: Environmental Pollution - June 1, 2023 Category: Environmental Health Authors: W Shu G W Price R Jamieson C Lake Source Type: research
Effect of biosolids amendment on the fate and mobility of non-steroidal anti-inflammatory drugs (NSAIDs) in a field-based lysimeter cell study
Environ Pollut. 2023 May 30;331(Pt 1):121939. doi: 10.1016/j.envpol.2023.121939. Online ahead of print.ABSTRACTNon-steroidal anti-inflammatory drugs (NSAIDs) are widely used globally to treat and prevent illness. Biosolids change physico-chemical characteristics of soil and can affect the mobility of NSAIDs. A field-based lysimeter study evaluated the effect of three rates (0, 7, and 28 Mg ha-1) of alkaline treated biosolids (ATB) on the leaching potential of naproxen (NPX), ibuprofen (IBF), and ketoprofen (KTF) over 34 days in a sandy loam textured soil. Although all three NSAIDs in the lysimeter cells vertically migrated...
Source: Environmental Pollution - June 1, 2023 Category: Environmental Health Authors: W Shu G W Price R Jamieson C Lake Source Type: research
EPH115 The Effect of Non-Steroidal Anti-Inflammatory Drugs on C-Reactive Protein Levels and Mortality in Patients with Sepsis
A recent in vitro study found that ibuprofen, naproxen, and ketorolac are competitive caspase inhibitors, a promising anti-inflammatory target for septic shock treatment. However, the impact of such NSAIDs on health outcomes among patients with sepsis is unknown. (Source: Value in Health)
Source: Value in Health - June 1, 2023 Category: International Medicine & Public Health Authors: B. Truong, J. Qian, J. Zheng, P. Zeng Source Type: research
Hypersensitivity to Non-Steroidal Anti-Inflammatory Drugs on a pediatric Portuguese cohort
Conclusions. The investigation of allergy to NSAID/paracetamol in children remains a challenge. In our population, ibuprofen was the most common NSAID reported. There were only 2 (4.3%) mild reactions on DPT. We could allow the use of the culprit NSAID/analgesic in 11 patients and an alternative one in 9 patients. This study highlights the importance of DPT in children for a correct diagnosis of NSAID hypersensitivity and selection of an alternative drug.PMID:37249059 | DOI:10.23822/EurAnnACI.1764-1489.299 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - May 30, 2023 Category: Allergy & Immunology Authors: M I T Silva J Cosme C Lorenzo J Virtuoso R Gomes E Pedro A M Neves A Lopes Source Type: research
The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
CONCLUSION: We found that rizatriptan (good tolerability profile with a dose of 5 mg) and sumatriptan (oral administration) had higher efficiency as compared to other triptans. Regardless of type or dose, all triptans are generally well tolerated by patients, but a few adverse effects such as light-headedness (sumatriptan), nasopharyngitis, and, muscular spasms (sumatriptan/ naproxen), somnolence, and dry mouth (rizatriptan), and dizziness (zolmitriptan group) were reported with the triptans.PMID:37209053 (Source: Indian Pediatrics)
Source: Indian Pediatrics - May 20, 2023 Category: Pediatrics Authors: Roshan Chanchlani Amit Agrawal Dalwinder Janjua Shaik Nida Hafsa Source Type: research
The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
CONCLUSION: We found that rizatriptan (good tolerability profile with a dose of 5 mg) and sumatriptan (oral administration) had higher efficiency as compared to other triptans. Regardless of type or dose, all triptans are generally well tolerated by patients, but a few adverse effects such as light-headedness (sumatriptan), nasopharyngitis, and, muscular spasms (sumatriptan/ naproxen), somnolence, and dry mouth (rizatriptan), and dizziness (zolmitriptan group) were reported with the triptans.PMID:37209053 (Source: Indian Pediatrics)
Source: Indian Pediatrics - May 20, 2023 Category: Pediatrics Authors: Roshan Chanchlani Amit Agrawal Dalwinder Janjua Shaik Nida Hafsa Source Type: research
Naproxen chemoprevention induces proliferation of cytotoxic lymphocytes in Lynch Syndrome colorectal mucosa
CONCLUSIONS: Our findings show that daily exposure of naproxen promotes T-cell proliferation in the colonic mucosa, which paves way for developing combination of immunoprevention strategies including naproxen for LS patients.PMID:37207208 | PMC:PMC10189148 | DOI:10.3389/fimmu.2023.1162669 (Source: Cancer Control)
Source: Cancer Control - May 19, 2023 Category: Cancer & Oncology Authors: Charles M Bowen Nan Deng Laura Reyes-Uribe Edwin Roger Parra Pedro Rocha Luisa M Solis Ignacio I Wistuba Valerie O Sepeda Lana Vornik Marjorie Perloff Eva Szabo Asad Umar Krishna M Sinha Powel H Brown Eduardo Vilar Source Type: research
