The First EVAR (Endovascular Abdominal Aortic Aneurysm Repair)
The whole field of endovascular repair and intervention has grown exponentially since the first endovascular repair of an abdominal aortic aneurysm (EVAR) was performed by Dr. Juan Parodi in 1990, but it took quite some time to be accepted as a standard of care. Today the endovascular approach is the preferred procedure to repair an AAA and this is because of the advances in medical device design and manufacturing and the dedication of physicians to this less invasive non-surgical approach, physicians who will be attending this year ’s Veith Symposium. (Source: Burts Stent Blog : The Voice in the Ear)
Source: Burts Stent Blog : The Voice in the Ear - November 13, 2018 Category: Medical Devices Source Type: blogs
Fight Aging! Newsletter, March 26th 2018
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - March 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 13th 2017
In conclusion, we have developed an effective PILs strategy to deliver the AUF1 plasmid to a specific target, and this system may be useful for the development of new anti-aging drugs.
Considering the Evidence for Vascular Amyloidosis as a Cause of Aging
https://www.fightaging.org/archives/2017/11/considering-the-evidence-for-vascular-amyloidosis-as-a-cause-of-aging/
The balance of evidence for the aging of the cardiovascular system suggests the following view. It starts off in the blood vessels, with the accumulation of senescent cells and cross-links. Cross-links directly stiffen these tissues, while...
Source: Fight Aging! - November 12, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cardiology MCQ Test 5
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Source: Cardiophile MD - October 22, 2017 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Health Affairs Web First: Significant Racial Disparities Found In Hospital Readmissions
This study will also appear in the July issue of Health Affairs.
(Source: Health Affairs Blog)
Source: Health Affairs Blog - June 21, 2017 Category: Health Management Authors: Lucy Larner Tags: Elsewhere@ Health Affairs Web First Source Type: blogs
Medtronic ’s Endurant II/IIs Stent Grafts Cleared in Europe for ChEVAR AAA Procedures
Medtronic received the EU CE Mark for its Endurant II/IIs stent grafts to be used to treat abdominal aortic aneurysms (AAA) using the ChEVAR technique (chimney technique in endovascular aortic aneurysm repair). ChEVAR can be particularly useful in timely situations to avoid having to produce patient customized branched and fenestrated stent grafts, as well as for use in patients with short aortic necks.
ChEVAR essentially relies on placing traditional stents or stent grafts linking the main artery with the side branches, and positioning the main stent graft within the aorta and pressing against the side branch stents (see...
Source: Medgadget - December 7, 2016 Category: Medical Equipment Authors: Editors Tags: Radiology Vascular Surgery Source Type: blogs
Does the increased frequency of repair of AAA in the United States reap benefits?
A popular meme is that the U.S. spends more on health care than other developed nations but has nothing to show for that spending. This is different from saying that the U.S. spends more, but achieves something, but the something it achieves is so little that it isn’t worth the public purse. The latter is difficult to assert because the asserter must then say how little is too little in regards to how much is spent, and why. It is easier believing the excess spending has no effect whatsoever, zilch in fact, because this absolves one from having to apply a value judgment on how much a life is worth. This meme, a convenien...
Source: Kevin, M.D. - Medical Weblog - December 2, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/dr-saurabh-jha" rel="tag" > Dr. Saurabh Jha < /a > Tags: Conditions Radiology Surgery Source Type: blogs
Two Nations Separated by 5.3 mm
By SAURABH JHA MD
A popular meme is that the U.S. spends more on healthcare than other developed nations but has nothing to show for that spending. This is different from saying that the U.S. spends more, but achieves something, but the something it achieves is so little that it isn’t worth the public purse. The latter is difficult to assert because the asserter must then say how little is too little in regards to how much is spent, and why. It is easier believing the excess spending has no effect whatsoever, zilch in fact, because this absolves one from having to apply a value judgment on how much a life is worth. This ...
Source: The Health Care Blog - November 26, 2016 Category: Consumer Health News Authors: at RogueRad Tags: OP-ED Physicians Uncategorized Source Type: blogs
Thresholds for Abdominal Aortic Aneurysm Repair in England and...
Thresholds for Abdominal Aortic Aneurysm Repair in England and the United States via Now@NEJMPosted oninfosnack. (Source: Kidney Notes)
Source: Kidney Notes - November 22, 2016 Category: Urology & Nephrology Authors: Joshua Schwimmer Source Type: blogs
Fight Aging! Newsletter, October 3rd 2016
In conclusion, in order to allow faithful and meaningful discoveries, future analysis of iPSCs and their derivatives should not shy away from mitochondrial genome monitoring and single-cell technology.
A Copy of the Self: Today's Airy Philosophy is Tomorrow's Practical Concern
https://www.fightaging.org/archives/2016/09/a-copy-of-the-self-todays-airy-philosophy-is-tomorrows-practical-concern/
The march of technology turns matters of philosophy into matters of practical action. The process of taking visions and making them concrete makes once airy hypotheticals relevant in everyday life. The theoria of t...
Source: Fight Aging! - October 2, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Calorie Restriction Reduces Age-Related Weakening of Blood Vessels
In this study, we subjected Apoe-/- mice to 12 weeks of CR and then examined the incidence of angiotensin II (AngII)-induced AAA formation. We found that CR markedly reduced the incidence of AAA formation and attenuated aortic elastin degradation in Apoe-/- mice. The expression and activity of Sirtuin 1 (SIRT1), a key metabolism/energy sensor, were up-regulated in vascular smooth muscle cells (VSMCs) upon CR. Importantly, the specific ablation of SIRT1 in smooth muscle cells abolished the preventive effect of CR on AAA formation in Apoe-/- mice. Mechanistically, VSMC-SIRT1-dependent deacetylation of histone H3 lysine 9 on ...
Source: Fight Aging! - September 26, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
DM / DNB Cardiology Entrance New Test Series 5
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Source: Cardiophile MD - August 6, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 7
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Source: Cardiophile MD - January 23, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 3
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Source: Cardiophile MD - January 17, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 2
This study reported 32 arrhythmic episodes in 24 patients. There was spontaneous recovery with abstinence from alcohol.
Reference
1. Ettinger PO, Wu CF, De La Cruz C Jr, Weisse AB, Ahmed SS, Regan TJ. Arrhythmias and the “Holiday Heart”: alcohol-associated cardiac rhythm disorders. Am Heart J. 1978 May;95(5):555-62.Question 14Diagnosis based on the echocardiogram:
AEbstein’s anomaly of tricuspid valveBNone of the aboveCEndomyocardial fibrosisDIdiopathic dilatation of right atriumQuestion 14 Explanation: Endomyocardial Fibrosis (EMF) is a type of restrictive cardiomyopathy. It is characterised by fibros...
Source: Cardiophile MD - January 16, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
