Concurrent gitelman syndrome-like tubulopathy and grave & #39;s disease
We describe a case of a 45-year-old man who presented with severe muscle weakness; the evaluation showed volume depletion, hypokalemia, hypomagnesemia, renal potassium and magnesium wasting, metabolic alkalosis, and hypocalciuria. He was also detected to have GD at the time of presentation. Genetic evaluation revealed a mutation in transient receptor potential melastatin 4 (TRPM4) gene. The clinical significance of this mutation in our patient remains unclear.
Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Rajasekaran Kishore Kumar Venkatesh Srimathy Rajeev A Annigeri Source Type: research
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