Crimean-Congo hemorrhagic fever virus vaccine: past, present, and future

Crimean-Congo hemorrhagic fever (CCHF) has been recognized as a tick-borne infection caused by a member of the Nairoviridae family within the Bunyavirales order, named CCHF virus. CCHF virus is a zoonotic virus, so transferred between vertebrates and humans. Therefore, vaccination in humans and animals might reduce the risk of infection. Currently, there are no globally licensed vaccines or therapeutics for CCHF. Although several studies have been performed on the production of the CCHF vaccine, any of these vaccines were not fully protective. Hence, the development of a new generation of vaccines could contribute to better management of CCHF. In this review, we will discuss on features of these vaccine candidates.
Source: Reviews in Medical Microbiology - Category: Microbiology Tags: VIROLOGY Source Type: research