The Effect of an EDTA-based Chelation Regimen on Patients With Diabetes Mellitus and Prior Myocardial Infarction in the Trial to Assess Chelation Therapy (TACT) [Original Articles]

Conclusions— Post–myocardial infarction patients with diabetes mellitus aged ≥50 demonstrated a marked reduction in cardiovascular events with EDTA chelation. These findings support efforts to replicate these findings and define the mechanisms of benefit. However, they do not constitute sufficient evidence to indicate the routine use of chelation therapy for all post–myocardial infarction patients with diabetes mellitus. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00044213.
Source: Circulation: Cardiovascular Quality and Outcomes - Category: Cardiology Authors: Tags: Cardiovascular Pharmacology, Secondary prevention, Type 2 diabetes, Chronic ischemic heart disease, Oxidant stress Original Articles Source Type: research