Risk factors for candidiasis as an intra-abdominal infection after gastrectomy in patients with gastric cancer

This study aimed to identify the microorganisms causing IAIs after gastrectomy and the risk factors for Candida-related IAI. The records of patients who underwent gastrectomy for gastric cancer between January 2009 and December 2019 at Shizuoka General Hospital were retrospectively collected. Patients with IAIs of grade 2 or higher as measured by the Clavien-Dindo classification were included in the analysis. The selected patients were divided into a Candida group and a non-Candida group according to the presence or absence of Candida as the causative organism. Fifty-six (4.1%) of 1379 patients were diagnosed with IAIs after gastrectomy. Fifty-two patients were included based on culture analyses. A total of 111 strains and 28 bacterial species were isolated in the initial culture test. Candida constituted 7.2% of all the identified pathogens. Regarding the risk factors for Candida-related IAI, a history of antimicrobial use and ≥4 postoperative days of IAI development were independent risk factors for Candida-related IAI.PMID:35491228 | DOI:10.7883/yoken.JJID.2021.893
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research