Association of recurrent mutations in BRCA1, BRCA2, RAD51C, PALB2, and CHEK2 with the risk of borderline ovarian tumor

ConclusionsResults suggest thatCHEK2(c.470T>C) may possibly play a role in the pathogenesis of BOT, but due to the low number of BOT patients, obtained results should be considered as preliminary. Larger more in-depth studies are required.
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research