Nrf2 deficiency attenuates atherosclerosis by reducing LOX-1-mediated proliferation and migration of vascular smooth muscle cells

CONCLUSIONS: Together, our data indicate that Nrf2 insufficiency is linked to attenuation of atherosclerosis, and could diminish the pathological process by blunting LOX-1-mediated proliferation and migration of VSMCs.PMID:35299056 | DOI:10.1016/j.atherosclerosis.2022.02.025

Source: Atherosclerosis - March 17, 2022 Category: Cardiology Authors: Hongliang Li Wenwen Zhuang Tianqing Xiong Won Sun Park Song Zhang Yiwen Zha Jiali Yao Fangfang Wang Yongqi Yang Yingrui Chen Linqian Cai Ling Ling Duonan Yu Jingyan Liang Source Type: research