Induction of Salivary Gland-Like Tissue by Induced Pluripotent Stem Cells In Vitro

Conclusion:IRF6 promotes salivary gland differentiation in urine-derived iPSCs, and its mechanism of promoting differentiation may be that IRF6 upregulates the expression of HAPLN1, CCL2, MSX2, ANXA1, CYP11A1, HES1 and LUM to promote epithelial differentiation.
Source: Tissue Engineering and Regenerative Medicine - Category: Biotechnology Source Type: research