Replication-related genes are upregulated in XP-A cells after UV-C irradiation

Xeroderma pigmentosum (XP) is hereditary disorder characterized by photosensitivity, predisposition to skin cancers of sun-exposed body sites and progressive neurologic symptoms in some cases. Cells from XP patients show higher sensitivity to ultraviolet radiation (UV) than normal cells.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research