Calciphylaxis After Aortic Valve Replacement in a Patient with End-Stage Renal Disease
In this study, we report a case of a patient on dialysis who presented necrotic lesions on the legs and penile ulceration 7 years after a mechanical aortic valve replacement. The diagnosis of calciphylaxis was not confirmed even after skin biopsy, and multidisciplinary management was not initiated until the patient was admitted with septic shock. Cardiovascular surgeons should be aware of warfarin-induced calciphylaxis, whose pathophysiology differs from that of atherosclerosis. Considering poor long-term survival of dialysis patients, mechanical valves should be reserved only for those patients whose estimated survival is longer than the time taken for a biological valve to deteriorate.PMID:35082944 | PMC:PMC8752931 | DOI:10.3400/avd.cr.21-00040
Source: Atherosclerosis - Category: Cardiology Authors: Kazunobu Hirooka Keisuke Anju Yoshihiro Moriyama Yuichi Araki Ekapot Bhunchet Ryoji Kinoshita Yohei Yamamoto Hidetoshi Uchiyama Masahiro Oonuki Hiroyuki Tanaka Source Type: research
More News: Cardiology | Cardiovascular | Cardiovascular & Thoracic Surgery | Coumadin | Dialysis | Heart | Heart Valve Surgery | Penile Biopsy | Septic Shock | Skin | Skin Biopsy | Study | Warfarin