Effect of Severe Renal Impairment on the Safety, Tolerability, and Pharmacokinetics of AMG 986

ConclusionsThe results of this study support the enrollment of HF patients with RI to clinical trials of AMG 986 without the need for dose adjustments.Trial Registration NumberNCT03318809 (registered: October 24, 2017).

http://link.springer.com/10.1007/s40268-021-00380-1

Source: Drugs in R&D - January 29, 2022 Category: Drugs & Pharmacology Source Type: research