The core four - A panel of immunohistochemistry markers to diagnose and subtype testicular germ cell tumors

Conclusions: Designing a novel concise and affordable IHC panel constituting OCT 3/4, CD117, GPC3, and CD30 has good sensitivity and specificity in differentiating seminomas, YST, and EC, respectively. Additional markers, namely β-HCG, can be used in identifying the choriocarcinoma component.

Source: Urology Annals - January 20, 2022 Category: Urology & Nephrology Authors: VN Ranjitha Rashmi Khemani B Vishal Rao Daphne Fonseca S Sudha Murthy Ashwin Giridhar Y Jayakarthik Rakesh Sharma KV V. N. Raju T Subramanyeshwar Rao Challa Sundaram Source Type: research