Altered brain functional network dynamics in classic trigeminal neuralgia: a resting-state functional magnetic resonance imaging study

ConclusionsThe present study indicated disrupted flexibility of brain topological organization under persistent noxious stimulation and further highlighted the important role of “dynamic pain connectome” regions (including DMN/CC/SN) in the pathophysiology of CTN from the temporal fluctuation aspect. Additionally, the findings provided supplementary evidence for current knowledge about the aberrant cortical-subcortical interaction in pain development.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research