Cyclosporine-induced leukoencephalopathy precipitated following interaction with ciprofloxacin

Divya Nagabushana, Supraja Chandrasekhar, Stalin Ramprakash, Gurudutt Avathi Venkatesha, Rajesh V HelavarJournal of Pediatric Neurosciences 2021 16(2):161-162A bone marrow transplant recipient on cyclosporine initiated on ciprofloxacin for a renal abscess presented with encephalopathy, right hemiparesis, and multiorgan dysfunction. Imaging revealed white matter signal changes characteristic of cyclosporine leukoencephalopathy. This case illustrates the potential drug interaction of cyclosporine with ciprofloxacin and the need to exercise caution while prescribing antibiotics with cyclosporine.
Source: Journal of Pediatric Neurosciences - Category: Neuroscience Authors: Source Type: research