Structural validation and dyadic child–parent measurement invariance of the celiac disease quality of life questionnaire
Conclusion Overall, with minor modifications, the Hebrew version of the CDDUX was found to be a valid measure of children’s celiac-related quality of life when measured across children’s self-reports and parent-proxy reports. The CDDUX provides meaningful measurement and allows child–parent comparison.
Conditions: Celiac Disease; Malabsorption Syndromes; Digestive System Disease; Intestinal Disease; Gastrointestinal Diseases; Gluten Sensitivity; Celiac Disease in Children Intervention: Dietary Supplement: Gluten Powder Sponsors: Boston Children's Hospital; Children's Hospital Colorado; Celiac Disease Foundation Not yet recruiting
Condition: Celiac Disease Intervention: Behavioral: Food for Thought Sponsors: Children's National Research Institute; Children's Hospital Colorado Not yet recruiting
World J Gastroenterol. 2021 Dec 21;27(47):8040-8046. doi: 10.3748/wjg.v27.i47.8040.ABSTRACTHelicobacter pylori (H. pylori) infection causes changes to the intestinal flora, such as small intestinal bacterial overgrowth, and increases gastric acid secretion-stimulating gastrointestinal hormones, mainly gastrin, due to a decrease in gastric acid caused by atrophic gastritis. In addition, the cellular components of H. pylori travel through the intestinal tract, so the bacterial infection affects the immune system. Therefore, the effects of H. pylori infection are observed not only in the stomach and the proximal duodenum but ...
ConclusionThis study implied a causal relationship between the Bifidobacterium genus and T1D and CeD, thus providing novel insights into the gut microbiota-mediated development mechanism of ADs.
To investigate the vasculature of the retina and choroid in children with celiac disease using optical coherence tomography angiography (OCTA).
ConclusionPatients with CD with more than 3 years of symptoms, more often have atypical presentation, anemia, pubertal delay, and more advanced histological changes. They also have fewer physician and gastroenterologist consultations. This underlines the need for proper awareness to ensure early diagnosis and treatment.
Olmesartan, an anti-hypertensive medication among the class of angiotensin II receptor blockers (ARB), has been rarely associated with severe sprue-like enteropathy. Patients have been reported to present with villous atrophy and symptoms that appear consistent with seronegative celiac disease. We here describe a case of olmesartan-induced enteropathy1.
Several groups have described a subset of CD8 T cells with immunosuppressive characteristics in inflammatory disease settings. The increased prevalence of a defined subset of CD8 T cells and correlation to disease has been reported in mouse and human autoimmune diseases, suggesting a protective role for select CD8 T cells in autoimmunity. We hypothesized that a dysregulated regulatory CD8 T cell (CD8 Treg) network was similarly involved in the pathology of autoimmune diseases of the gut, including Celiac disease, Crohn ’s, and Ulcerative Colitis.
CONCLUSIONS: In individuals with chronic diarrhea for more than three months, the prevalence of celiac disease was determined to be 12.2% (n=23). There was a statistically significant difference between those with a positive family history of CD and those who did not have the condition.PMID:35047307 | PMC:PMC8760010 | DOI:10.7759/cureus.20495
iar Churruca Arrate Lasa The present work aimed to analyze, through the GlutenFreeDiet digital platform, the evolution over one year of the nutritional status, dietary profile and symptoms present among celiac people on a gluten-free diet (GFD) while receiving individualized dietary advice. Twenty-seven adults and thirty-one celiac children/adolescents participated in the study. This was then followed up by three visits, at diagnosis, and after 3 and 12 months (vt0, vt3 and vt12). Participants filled out dietary and gastrointestinal symptoms questionnaires. All patients received written personalized dietary advice fr...