Multiple sites of calciphylaxis in a patient with chronic renal failure.
We report a pre-hemodialysis (HD) patient with acute renal failure and biopsy-proven calciphylaxis involving multiple cutaneous sites with calcification of the perineal area resulting in dry gangrene of the penis that necessitated a partial penectomy. The patient had elevated serum calcium, phosphorous and parathyroid hormone level of 612 pg/mL. The same patient suffered subsequently from a calcium embolus that occluded his left ophthalmic artery and resulted in left eye blindness. Calciphylaxis is a devastating phenomenon and physicians should have a high clinical suspicion for it in HD patients as well as in patients with late stages of chronic kidney disease. PMID: 25758887 [PubMed - in process]
Objective: To determine the cumulative 30-day and 1-year mortality as well as personal independence after hip fracture in patients on hemodialysis. Design: Prospective, observational cohort study with matched controls. Setting: One teaching hospital, one metropolitan trauma center, one peripheral hospital. Patients and Intervention: Study group: a consecutive cohort of 64 patients with end-stage renal disease receiving chronic hemodialysis who had undergone surgery for a trochanteric or femoral neck fracture from June 2008 to November 2016. Control group: subjects without end-stage renal disease who underwent su...
Conclusions: This retrospective cohort study demonstrates that both ESRD and CKD patients have worse outcomes compared to patients with no kidney disease after HA for FNF. Level of Evidence: Prognostic Level III. See instructions for authors for a complete description of levels of evidence.
Dialysis is usually needed when patients lose about 85% to 90% of their kidney function or when they develop end-stage kidney failure.
Publication date: Available online 20 October 2019Source: Best Practice &Research Clinical HaematologyAuthor(s): Richard J. JonesAbstractClose HLA matching of donors and recipients has been the dogma for successful allogeneic blood or marrow transplantation (BMT), to limit the complications of graft rejection and graft-versus-host disease (GVHD). However, many patients in need, especially those in certain racial and ethnic groups such as African-Americans and Hispanics, are unable to find matches despite increased availability of unrelated donors. Unfortunately, despite many early attempts to develop safe, related hapl...
Authors: Novell M, Rico N, Blondeau P, Blasco M, Maceira A, Bedini JL, Andrade FJ, Maduell F PMID: 31627974 [PubMed - as supplied by publisher]
Authors: Martín Hidalgo-Barquero MV, Ruiz-Calero Cendrero RM, Cancho Castellano B, Cid Parra MC, Galán González J PMID: 31627973 [PubMed - as supplied by publisher]
Mayo Clinic researchers say prior studies show prostate cancer risk is higher in Western nations that rely on dairy as a main source of calcium compared to Asian countries that rely more on plant-based foods for it.
Conditions: Chronic Kidney Diseases; Blood Pressure; Hyperemia; Vasoconstriction Interventions: Drug: Curcumin; Other: Placebo Sponsor: Nicholas Kruse Not yet recruiting
Condition: Anemia in Incident Dialysis Patients Interventions: Drug: Roxadustat; Drug: Epoetin Alfa Sponsor: Second Xiangya Hospital of Central South University Recruiting
Condition: Transplant; Decision-making Interventions: Other: Total Survival; Other: Stratified Transplant Survival Sponsor: Carnegie Mellon University Not yet recruiting