Case Report: Dengue Hemorrhagic Fever with Ischemic Stroke

We report a case of ischemic stroke in a patient with dengue hemorrhagic fever. A 52-year-old previously healthy male presented with a history of fever for 2 days, and left-sided weakness and numbness of sudden onset. MRI scanning showed a right-sided thalamic lacunar infarct. Diagnosis of dengue fever was made based on leuco-thrombocytopenia, positive dengue nonstructural protein-1 (NS-1) antigen, and positive dengue IgM antibodies. Severity of limb weakness correlated with the critical phase of dengue hemorrhagic fever (DHF). He was discharged home with good recovery from neurological symptoms and disability. Strokes are rare in dengue, and are mainly hemorrhagic strokes related to thrombocytopenia. Ischemic stroke is even rarer. More evidence is needed for confirmation of dengue as a pathogenic mechanism of ischemic stroke.PMID:34781261 | DOI:10.4269/ajtmh.21-0618

Source: The American Journal of Tropical Medicine and Hygiene - November 15, 2021 Category: Tropical Medicine Authors: B W M K E Basnayake K G S K Somaratne C U Goonetilleke P M Y I Tilakaratna U K Ranawaka Source Type: research