Risk of suicide among individuals with a history of childhood cancer - Barnes JM, Johnson KJ, Grove JL, Srivastava AJ, Osazuwa-Peters N, Perkins SM.

The objectives of this study were to assess whether childhood cancer survivors are at in...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

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ConclusionThe DCE-MRI radiomics model, especially image features extracted from the delayed phases, can help improve the performance in predicting TILs. The radiomics nomogram is effective in predicting TILs in breast cancer.Key Points•Radiomics features extracted from DCE-MRI, especially delayed phase images, help predict TIL levels in breast cancer.•We developed a nomogram based on MRI to predict TILs in breast cancer that achieved the highest AUC of 0.950.
Source: European Radiology - Category: Radiology Source Type: research
ConclusionWe observed strong reproducibility in the assessment of PI-QUAL between two radiologists with high expertise in prostate mpMRI. At present, PI-QUAL offers clinicians the only available tool for evaluating and reporting the quality of prostate mpMRI in a systematic manner but further refinements of this scoring system are warranted.Key Points•Inter-reader agreement for each single Prostate Imaging Quality (PI-QUAL) score (i.e., PI-QUAL 1 to PI-QUAL 5) was strong, with weighted kappa = 0.85 (95% confidence intervals: 0.51 – 1) and percent agreement = 84%.• Interobserver  agreement was strong wh...
Source: European Radiology - Category: Radiology Source Type: research
This study was designed to compare the detection of subtle lesions (calcification clusters or masses) when using the combination of digital breast tomosynthesis (DBT) and synthetic mammography (SM) with digital mammography (DM) alone or combined with DBT.MethodsA set of 166 cases without cancer was acquired on a DBT mammography system. Realistic subtle calcification clusters and masses in the DM images and DBT planes were digitally inserted into 104 of the acquired cases. Three study arms were created: DM alone, DM with DBT and SM with DBT. Five mammographic readers located the centre of any lesion within the images that s...
Source: European Radiology - Category: Radiology Source Type: research
No abstract available
Source: Journal of the American Academy of Physician Assistants - Category: Primary Care Tags: Quick Recertification Series Source Type: research
The number of people living with chronic immunosuppression is increasing in the United States. Patients with HIV, those who have had bone marrow or solid organ transplants, and patients taking biologics for autoimmune diseases are at increased risk for skin cancer. Skin cancer in these patients is more aggressive and more likely to metastasize and cause death. Medications and individual risk factors such as sex, age, and ethnicity are independent risk factors for the development of skin cancer. Routine screening and aggressive treatment of actinic keratoses and nonmelanoma skin cancers can reduce patients' skin cancer burd...
Source: Journal of the American Academy of Physician Assistants - Category: Primary Care Tags: CME: Primary Care Source Type: research
Amber Capone had become afraid of her husband. The “laid-back, bigger than life and cooler than cool” man she’d married had become isolated, disconnected and despondent during his 13 years as a U.S. Navy SEAL. Typically, he was gone 300 days of the year, but when he was home, Amber and their two children walked on eggshells around him. “Everyone was just playing nice until he left again,” Amber says. In 2013, Marcus retired from the military. But life as a civilian only made his depression, anger, headaches, anxiety, alcoholism, impulsivity and violent dreams worse. Sometimes he’d get up...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs feature Magazine Mental Health Source Type: news
In this study, a link between mitochondrial changes and infant temperament has also been suggested. Maternal psychosocial stress and lifetime trauma have been associated with decreased mitochondrial DNA copy number in the placenta (115, 116).IndividualityChronic stress links changes in the epigenetic landscape with health conditions (117). Different cell types are characterized by distinct patterns of gene expression due to developmental, environmental, physiological, and pathological reasons (117). Epigenetic mechanisms affect gene function in a dynamic way as a result of different environmental exposures during fetal dev...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health work...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
BY SUNEEL RATAAN The Ketamine Papers serves as an essential window into the rapidly accelerating application of the anesthetic cum party drug ketamine to individuals with disorders such as treatment-resistant depression and post-traumatic stress disorder (PTSD). In addition, the book’s release coincides with other psychedelics, MDMA (aka ‘Ecstasy’) and psilocybin, being cleared for late-phase clinical trials as therapeutic adjuncts for the treatment and – dare we say – cure of those and related disorders, a process that will still take some years. Given what seems to be an increasing explosio...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Ecstasy LSD MDMA Psilocybin PTSD Source Type: blogs
Why do individuals commit suicide? Despite its prevalence, suicide remains highly stigmatized and survivors of suicide often suffer in silence in fear of being judged and criticized. This paper will first examine the prevalence of suicide, focusing on gender, culture, method, and mental illness. Further, this paper aims to explore the impact suicide has on parents, siblings, children, peers, spouses, attempters, and therapist survivors. A thorough examination of the areas of greatest difficulty each survivor group experiences will be done. Finally, a thorough review of treatment guidelines and efficacy will be explored. Wi...
Source: Psych Central - Category: Psychiatry Authors: Tags: Caregivers Children and Teens Depression Disorders Family General Grief and Loss Psychology Psychotherapy Suicide Major Depressive Disorder Suicidal Ideation Source Type: news
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