Inhibition of the Immunoproteasome Subunit LMP7 Ameliorates Cerebral White Matter Demyelination Possibly via TGF < em > β < /em > /Smad Signaling

CONCLUSIONS: The possible mechanism underlying this was attributed to that the immunoproteasome regulates TGFβ/Smad signaling-mediated neuroinflammation and oligodendrocyte remyelination.PMID:34675988 | PMC:PMC8526201 | DOI:10.1155/2021/6426225

Source: Evidence-based Complementary and Alternative Medicine - October 22, 2021 Category: Complementary Medicine Authors: Xingyong Chen Nannan Yao Zejing Lin Yinzhou Wang Source Type: research