Impact of preprocedural biological markers on 10-year mortality in the SYNTAXES trial

CONCLUSIONS: Preprocedural biomarkers, such as CRP and HbA1c, are associated with long-term mortality post revascularisation, regardless of the revascularisation technique. Conventional lipidic biomarkers associated with high-risk of cardiovascular events seem to be effectively mitigated by the long-term use of statins, whereas the non-use of statins was a factor of a worse prognosis, emphasising the importance of pharmacological treatment.TRIAL REGISTRATION: SYNTAXES ClinicalTrials.gov reference: NCT03417050. SYNTAX ClinicalTrials.gov reference: NCT00114972.PMID:34669586 | DOI:10.4244/EIJ-D-21-00415

Source: EuroIntervention - October 20, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Hironori Hara Hideyuki Kawashima Masafumi Ono Kuniaki Takahashi Michael J Mack David R Holmes Marie-Claude Morice Piroze M Davierwala Friedrich W Mohr Daniel J F M Thuijs Arie Pieter Kappetein Neil O'Leary David van Klaveren Yoshinobu Onuma Patrick W Serr Source Type: research