Off-resonance saturation as an MRI method to quantify mineral- iron in the post-mortem brain

CONCLUSIONS: Off-resonance saturation is an effective way to detect iron in gray matter structures and partially mitigate for the presence of myelin. If a reference region with little iron is available in the tissue, the method can produce quantitative iron maps. This method is applicable in the study of diseases characterized by brain iron accumulation and can complement existing iron-sensitive parametric methods.PMID:34655092 | DOI:10.1002/mrm.29041

Source: Magnetic Resonance in Medicine - October 16, 2021 Category: Radiology Authors: Lucia Bossoni Ingrid Hegeman-Kleinn Sjoerd G van Duinen Marjolein Bulk Lena H P Vroegindeweij Janneke G Langendonk Lydiane Hirschler Andrew Webb Louise van der Weerd Source Type: research