Impact of the inversion time on regional brain perfusion estimation with clinical arterial spin labeling protocols

ConclusionsTI influences ASL perfusion estimates with a region-dependent effect. The presence of intraluminal arterial signal in PTAs and the longer arterial transit time in the DTAs (including watershed areas) may account for the TI-dependent differences. Watershed areas exhibiting a lower perfusion signal at short TIs (~  1500 ms) should not be misinterpreted as focal hypoperfused areas.
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - Category: Materials Science Source Type: research