Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid- β plaques

Increasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer ’s disease comes from molecular and functional studies in rodent models. Howeve...

Source: Molecular Neurodegeneration - September 25, 2021 Category: Neurology Authors: Pranav Preman, Julia TCW, Sara Calafate, An Snellinx, Maria Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison M Goate, Bart De Strooper and Amaia M Arranz Tags: Methodology Source Type: research