Prevalence and multidrug resistance in Salmonella enterica Typhimurium: an overview in South East Asia

AbstractAcute/chronic gastroenteritis is caused by a few serovars ofSalmonella enterica. Among different serovars,S. enterica Typhimurium is a potent pathogen that contributes significantly to self-limiting diarrhea related mortality worldwide. With no successful vaccine in hand against this pathogen, antibiotics are used as for gold standard for treatment againstSalmonella induced gastroenteritis. Indispensably, rise in multi drug resistance againstSalmonella Typhimurium poses challenge to treatment options. South East Asia, with 11 different countries, stands 3rd as super region for global burden ofSalmonella induced gastroenteritis. In this review, we made an attempt to discuss on prevalence and multidrug resistance inSalmonella Typhimurium in 11 countries of South East Asia —the issue that has not been seriously addressed so far. By thorough analysis of reported data, we found varying frequencies for prevalence ofSalmonella Typhimurium as well as subtle evidences on resistance of this pathogen to multiple antibiotics in different countries. Vietnam ranked top in terms of reports for prevalence and antimicrobial resistance. However, in countries such as Brunei and Timor Leste, no study has been performed so far to track the frequency of incidence and drug resistance of this pathogen. Our review, the first of its kind, emphasizes that, although the pathogen was not found as dominant serovar in South East Asia in last 20  years unlike sub-Saharan Africa, it may be still c...
Source: World Journal of Microbiology and Biotechnology - Category: Microbiology Source Type: research