Global Familial hypercholesterolemia Studies Collaboration (FHSC) highlights the challenges of care

Familial hypercholesterolemia (FH) is a common inherited condition, affecting about one in 300 people worldwide, and is characterised by elevated levels of low-density lipoprotein cholesterol (LDL-C) from birth [1 –3]. If untreated, this burden of lifelong high LDL-C levels predisposes to premature atherosclerotic cardiovascular disease (ASCVD), with individuals often experiencing their first myocardial infarction during middle-age [1]. However, if detected early – ideally during childhood – with prompt initiation of guideline-recommended lipid lowering therapy, individuals with this condition can live a normal, healthy life [4].
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research