Plaque Characteristics on CT Angiography Do Not Improve the Ability to Predict Hemodynamic Instability During and After Carotid Angioplasty and Stenting

Conclusions: Individuals without a previous contralateral endarterectomy and/or history of diabetes are at lower risk of hemodynamic instability. The addition of computed tomography angiographic variables does not improve this prediction. Future prospective, randomized work is required to improve our ability to identify and treat individuals at high risk of instability during carotid angioplasty and stenting.
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research

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AS CONCERNS about disease spread, a growing body of experts are investigating which unknown health boosters could pave the way to a longer lifespan. In the pursuit of longevity, one lesser-known herb has been shown to be highly effective.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Environ Sci Pollut Res Int. 2022 Jan 15. doi: 10.1007/s11356-022-18534-2. Online ahead of print.ABSTRACTDiabetes mellitus (DM) is a worldwide ailment which leads to chronic complications like cardiac disorders, renal perturbations, limb amputation and blindness. Type one diabetes (T1DM), Type two diabetes (T2DM), Another types of diabetes, such as genetic errors in function of β-cell and action of insulin, cystic fibrosis, chemical-instigated diabetes or following tissue transplantation), and pregnancy DM (GDM). In response to nutritional ingestion, the gut may release a pancreatic stimulant that affects carbohydrate ...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Source Type: research
J Nat Med. 2022 Jan 15. doi: 10.1007/s11418-021-01602-1. Online ahead of print.ABSTRACTIn diabetes, interactions between AGEs (advanced glycation end products) and RAGEs (receptors of AGEs) are responsible for chronic complications and the current work reports the potential of ursolic acid as a RAGE inhibitor. The three-dimensional crystal structure of RAGE was first docked with target molecules by 'AutodockVina' using GROMOS 96 4381 parameters. Druggability and pharmacokinetic properties were calculated from the SwissADME server. In vitro bovine serum albumin (BSA)-glucose fluorescence and BSA-methylglyoxal fluorescence a...
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
Biol Trace Elem Res. 2022 Jan 15. doi: 10.1007/s12011-021-02938-1. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a complex and progressive neurodegenerative disease with impaired synapse, imbalanced mineral metabolism, protein mis-folding and aggregation. Bis(ethylmaltolato)oxidovanadium(IV) (BEOV), an organic bioactive vanadium compound with low toxicity and high bioavailability, has been studied as therapeutic agent against tuberculosis and diabetes. However, its neuroprotective effects have rarely been reported. Therefore, in this study, the potential application of BEOV in intervening AD cognitive dysfuncti...
Source: Biological Trace Element Research - Category: Biology Authors: Source Type: research
DIABETES is characterised by high blood sugar levels. This is caused by problems with insulin production in the body. The most important aspect of diabetes management is blood sugar control. There's a golden liquid that can "significantly" reduce blood sugar.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: Patient Preference and Adherence - Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
ConclusionIVIM-derivedD and DTI-derived FA values were better than other parameters for evaluating early kidney impairment of diabetes. The single indicator FA andD performed as well as the combined diagnostic indicator in the medulla for differentiating the microalbuminuria subgroup from the control group.Key Points• We speculated that early renal progression in type 2 diabetes result from restricted tubular flow and kidney tubule dysregulation may precede or at least accompany abnormal glomerular changes.• In medulla, the AUC values of FA and D and the combination of FA and D obtained by comparing the microalbu...
Source: European Radiology - Category: Radiology Source Type: research
AbstractThe timing pattern in which dipeptidyl-peptidase IV inhibitors (DPP4i) confer the risk of bullous pemphigoid (BP) is unknown. To investigate the odds of BP following exposure to DPP4i and to perform a duration-response analysis evaluating the risk of BP in relation to the duration of exposure to the culprit drug. A population-based nested case –control study was performed comparing diabetic patients with BP (n = 1458) with age-, sex- and ethnicity-matched diabetic control subjects (n = 6051) with respect to the prevalence of exposure to DPP4i. Adjusted odds ratios (ORs) were estima...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
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