Insulin-like growth factor-2 does not improve behavioral deficits in mouse and rat models of Angelman Syndrome

ConclusionsDespite a few observed effects of IGF-2, our results taken together indicate that IGF-2 treatment does not profoundly improve behavioral deficits in mouse or rat models of AS. These findings shed cautionary light on the potential utility of acute systemic IGF-2 administration in the treatment of AS.
Source: Molecular Autism - Category: Molecular Biology Source Type: research