Auditory Oddball Responses Across the Schizophrenia-Bipolar Spectrum and Their Relationship to Cognitive and Clinical Features

CONCLUSIONS: Neural deviations during auditory processing are related to psychosis history and bipolar disorder. There is a powerful transdiagnostic relationship between severity of these neural deviations and general cognitive performance. These results have implications for understanding the neurobiology of clinical syndromes across the schizophrenia-bipolar spectrum that may have an impact on future biomarker research.PMID:34407624 | DOI:10.1176/appi.ajp.2021.20071043

Source: The American Journal of Psychiatry - August 19, 2021 Category: Psychiatry Authors: David A Parker Rebekah L Trotti Jennifer E McDowell Sarah K Keedy S Kristian Hill Elliot S Gershon Elena I Ivleva Godfrey D Pearlson Matcheri S Keshavan Carol A Tamminga Brett A Clementz Source Type: research