Insight into the cardiovascular mechanisms of blood pressure lowering effect of gitogenin: a steroidal saponin

Conclusion: These findings indicate that antihypertensive effect of gitogenin is the outcome of vascular and cardiac effects; agonistic effect on vascular M3 and cardiac M2 receptors; and being more selective for M2. Increase in the rate of atrial contraction might be of clinical importance.PMID:34396877 | DOI:10.1080/10641963.2021.1950748
Source: Clinical and Experimental Hypertension - Category: Cardiology Authors: Source Type: research