Voclosporin (Lupkynis) for Lupus Nephritis

Date: August 23, 2021 Issue #:  1631Summary:  Voclosporin (Lupkynis– Aurinia), an oral calcineurin inhibitor, has been approved by the FDA for use in combination with the antimetabolite immunosuppressant mycophenolate mofetil (Cellcept, and generics) and a corticosteroid for treatment of adults with active lupus nephritis. It is the first calcineurin inhibitor to be approved in the US for this indication. Tacrolimus (Prograf, and others) and cyclosporine (Neoral, and others), the other available systemic calcineurin inhibitors, are approved for prophylaxis of organ rejection in transplant patients.
Source: The Medical Letter - Category: Drugs & Pharmacology Authors: Tags: Abatacept Azathioprine belimumab Benlysta Cellcept corticosteroids Cyclophosphamide Cyclosporine Cytoxan Imuran Lupkynis Lupus Mycophenolate mofetil Neoral Orencia Procytox Prograf Rituxan Rituximab Tacrolimus voclo Source Type: research