New carotid plaque, but not the progression of intima-media thickness, predicts the progression of high-risk coronary plaque

Background Carotid intima-media thickness (CIMT) is regarded as a controversial risk marker for cardiovascular disease (CVD). We aimed to evaluate the role of CIMT and carotid plaque progression as predictors for the progression of coronary plaque and compositions. Methods In the Garlic 4 study, asymptomatic patients with intermediate CVD risk (Framingham risk score 6–20%) were recruited for a serial carotid ultrasound, and coronary artery calcium score (CAC)/coronary computed tomography angiography (CCTA) studies for subclinical atherosclerosis at a baseline and 1 year. The association between progression of quantitatively measured coronary plaque compositions and the progression of CIMT/carotid plaque was analyzed. A P value
Source: Coronary Artery Disease - Category: Cardiology Tags: Diagnosis and Prevention of CAD Source Type: research