HIF-1 < em > α < /em > RNAi Combined with Asparagus Polysaccharide Exerts an Antiangiogenesis Effect on Hepatocellular Carcinoma In Vitro and In Vivo

CONCLUSION: Our study indicates that HIF-1α RNAi combined with ASP inhibits angiogenesis in HCC via the PI3K and MAPK signaling pathways. Thus, we suggest that this combination may be an effective method for the comprehensive treatment of HCC, which may provide new ideas for the treatment of other malignant tumors.PMID:34335854 | PMC:PMC8324350 | DOI:10.1155/2021/9987383

Source: Evidence-based Complementary and Alternative Medicine - August 2, 2021 Category: Complementary Medicine Authors: Tingting Zhu Ziwei Cheng Xiaolin Peng Dongwei Xing Minguang Zhang Source Type: research