Pierre Vanderhaeghen awarded for his pioneering research
(Spanish National Research Council (CSIC)) The jury of the 10th edition of the Remedios Caro Almela Prize for Research in Developmental Neurobiology has decided to award this prize to Pierre Vanderhaeghen, director of the stem cell and developmental neurobiology laboratory of the VIB-KU Leuven Center for Research on the Brain and its Diseases (Belgium).
TheEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLAhas been awarded $5 million by the California Institute for Regenerative Medicine, the state ’s stem cell agency, to train young scientists and physicians to become leaders in the stem cell and regenerative medicine field.The five-year grant will enable the center to expand its Stem Cell Training Program, which was established in 2006 and funded by CIRM until 2015, when the agency changed its funding priorities. Since then, the program has been sustained by philanthropy. With the passage of Proposition 14 last fall, however, CIRM ha...
Conclusiones: Se logró establecer un protocolo de aislamiento y expansión celular, con alta tasa de éxito de una población de DPSCh.Resumo Objetivos: Estabelecer e implementar um protocolo simplificado para a extra ção, isolamento primário e cultura de células-tronco da polpa dentária humana (DPSCh). Analise as células isoladas quantitativa e qualitativamente. Metodologia: 10 terceiros molares saudáveis doados por pacientes que frequentaram a Faculdade de Odontologia UdelaR e deram consentimento por escrito foram processados antes ...
Condition: Plasma Cell Leukemia Intervention: Drug: Daratumumab Sponsor: Assistance Publique - Hôpitaux de Paris Not yet recruiting
One platform, 70 diseases and $72 million — these underpin the launch of Garuda Therapeutics, a new stem cell startup founded by Harvard professor Dhvanit Shah.
Conclusion: Rapid tumor CD133 detection and selectivity were demonstrated in vitro and in vivo with PET using the specific CD133 binding peptide 68Ga-DOTA-LS7. A robust correlation was detected in vivo between tumor signals from mouse xenograft models with different cell lines and CD133 expression. The favorable characteristics of 68Ga-DOTA-LS7, such as convenient synthesis and specific uptake, warrant its further investigation for CD133 expression imaging.
In conclusion, mesenchymal stem cells-derived secretome could be further explored for the management of Parkinson's disease.PMID:34553608 | DOI:10.2217/rme-2021-0018
This study provides new insights into the mechanisms and appropriate risk management of 4-NP.
Dalton Trans., 2021, Accepted Manuscript DOI: 10.1039/D1DT02909F, PerspectiveYingsi Li, Boxin Liu, Hongdong Shi, Yi Wang, Qi Sun, Qianling Zhang With the highest incidence, breast cancer ranks as the leading cause of cancer deaths among women in the world. Tumor metastasis and is the major contributor of high mortality in... The content of this RSS Feed (c) The Royal Society of Chemistry
g Yeng Looi Insight into cancer signaling pathways is vital in the development of new cancer treatments to improve treatment efficacy. A relatively new but essential developmental signaling pathway, namely Hedgehog (Hh), has recently emerged as a major mediator of cancer progression and chemoresistance. The evolutionary conserved Hh signaling pathway requires an in-depth understanding of the paradigm of Hh signaling transduction, which is fundamental to provide the necessary means for the design of novel tools for treating cancer related to aberrant Hh signaling. This review will focus substantially on the canonical Hh...
Autophagy is a highly conserved process for maintaining cellular homeostasis. Upregulation of autophagy promotes metastasis by promoting the cancer stem cell state while also stimulating tumor cell migration and invasion. We hypothesized that autophagy upregulation would be critical for cancer stem cell maintenance as well as cellular migration and invasion in thyroid cancer.