International study of rare childhood cancer finds genetic clues, potential for tailored therapy

(NIH/National Cancer Institute) In children with rhabdomyosarcoma, or RMS, a rare cancer that affects the muscles and other soft tissues, the presence of mutations in several genes, including TP53, MYOD1, and CDKN2A, appear to be associated with a more aggressive form of the disease and a poorer chance of survival. This finding is from the largest-ever international study on RMS, led by scientists at the National Cancer Institute ’ s (NCI) Center for Cancer Research, part of the National Institutes of Health.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news