Diabetes and the Gut Microbiome
Summary: Gut dysbiosis in diabetes mellitus is associated with decreased short-chain fatty acids and epithelial barrier disruption. Microbial-derived toxins move across the “leaky gut” and incur systemic inflammation and insulin resistance. In children, gut dysbiosis has been associated with risk of developing type 1 diabetes mellitus. In animal models, the obesity phenotype is transferable via microbiota transplantation. Plant-based low protein diets and certain a nti-diabetic drugs have been associated with positive microbiome effects.
Source: Seminars in Nephrology - Category: Urology & Nephrology Authors: Wei Ling Lau, Tiffany Tran, Connie M. Rhee, Kamyar Kalantar-Zadeh, Nosratola D. Vaziri Source Type: research
More News: Children | Diabetes | Diabetes Mellitus | Diabetes Type 1 | Diets | Eating Disorders & Weight Management | Endocrinology | Insulin | Nutrition | Obesity | Transplants | Urology & Nephrology