Transient elastography correlated to four different histological fibrosis scores in children with liver disease

Conclusion: TE shows a good correlation to the histological findings in children with hepatopathy, independent of the used histological scoring system.What is Known:•The current gold standard for detecting liver fibrosis is liver biopsy. Novel non-invasive ultrasound-based methods are introduced to clinical diagnostics.•Most histological scores have been developed and evaluated in adult populations and for only one specific liver disease.What is New:•Transient elastography (TE) in children showed a good correlation to fibrosis severity irrespective of the utilized histological scoring system.•The aspartate aminotransferase-to-platelet ratio (APRI) showed no correlation with different stages of liver fibrosis in children.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research