Renal manifestations in children with neurofibromatosis type 1

Conclusion: Hypertension, urinary tract anomalies, and impaired renal function were more common in NF1 patients than healthy controls. Regular blood pressure measurements and evaluation of urinary tract and kidney function are essential for NF1 patients.What is Known:• NF1 is most commonly associated with systemic hypertension due to renal artery vasculopathy and the development of a pheochromocytoma.• Hydronephrosis and bladder involvement have been documented in NF1.What is New:• Renal glomerular and tubular functions may be affected in NF1.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research