Lipopolysaccharide promotes metastasis via acceleration of glycolysis by the nuclear factor- κB/snail/hexokinase3 signaling axis in colorectal cancer

ConclusionLPS activates inflammasomes in cancer cells through NF- κB and promotes metastasis through glycolysis enhanced by the NF-κB/Snail/HK3 signaling pathway in CRC. Metformin could prevent this effect of LPS.
Source: Cancer and Metabolism - Category: Cancer & Oncology Source Type: research