Estrogen Receptor Is Expressed in Uveal Melanoma: A Potential Target for Therapy

Conclusions and Relevance: Potentially actionable ER expression is present in greater than half of UM cases by IHC. Gene expression ofESR1 andESR2 was elevated in a subset of UM tumors with poor prognostic features. These data provide a rationale to evaluate ER as a potential target for therapy in UM.Ocul Oncol Pathol
Source: Ocular Oncology and Pathology - Category: Opthalmology Source Type: research