Genetic etiologies associated with infantile hydrocephalus in a Chinese infantile cohort

CONCLUSIONS: Our study showed heterogeneous genetic etiologies in an IHC cohort. It is essential to perform genetic testing on IHC patients who have unclear clinical etiology, and genes associated with metabolic disorders, brain abnormalities, and genetic syndromes should be noted. In addition, when aiming to discover IHC susceptibility genes, genes that might influence the signaling pathways involved in IHC formation should be prioritized.PMID:33914258 | DOI:10.1007/s12519-021-00429-w

Source: World Journal of Pediatrics : WJP - April 29, 2021 Category: Pediatrics Authors: Hong-Fang Mei Xin-Ran Dong Hui-Yao Chen Yu-Lan Lu Bing-Bing Wu Hui-Jun Wang Guo-Qiang Cheng Lai-Shuan Wang Yun Cao Lin Yang Wen-Hao Zhou Source Type: research