P047  An unusual case of dermatomyositis with co-existent anti-GAD and anti-NXP2 antibody positivity

Conclusion GAD antibodies are known to be associated with many disorders including diabetes and stiff person syndrome and can recognise different epitopes in various diseases. This is the first documented case of GAD occurring in a DM patient, in the presence of NXP2 antibodies. IVIG is used to treat both s tiff man syndrome and refractory DM. It is possible that the combination of GAD and NXP2 contributed to the pathogenesis and severity of the clinical presentation in this case.Disclosure K. Beharry: None.G. Barminski: None.D. De Lord: None.
Source: Rheumatology - Category: Rheumatology Source Type: research