Viruses, Vol. 13, Pages 744: High Incidence of Zika or Chikungunya Infection among Pregnant Women Hospitalized due to Obstetrical Complications in Northeastern Brazil —Implications for Laboratory Screening in Arbovirus Endemic Area

Viruses, Vol. 13, Pages 744: High Incidence of Zika or Chikungunya Infection among Pregnant Women Hospitalized due to Obstetrical Complications in Northeastern Brazil—Implications for Laboratory Screening in Arbovirus Endemic Area Viruses doi: 10.3390/v13050744 Authors: Iracema J. A. A. Jacques Leila Katz Marília A. Sena Ana B. G. Guimarães Yasmim L. Silva Gabriela D. M. Albuquerque Raisa O. Pereira Camila A. M. C. de Albuquerque Maria Almerice L. Silva Paula A. S. Oliveira Maria de Fátima P. M. Albuquerque Marli T. Cordeiro Ernesto T. A. Marques Rafael F. O. França Celina M. T. Martelli Priscila M. S. M. S. Castanha Cynthia Braga The diagnostic of arbovirus-related obstetric complications in high-risk pregnancy and childbirth care is challenging, especially in endemic areas. We conducted a prospective study to track active or recent Zika (ZIKV), dengue (DENV), or chikungunya (CHIKV) virus infection among hospitalized pregnant women (PW) with obstetric complications in a hospital at the epicenter of Zika outbreak and ZIKV-related microcephaly in Brazil. Clinical data and blood samples were collected at enrollment and 10 days after the admission of study participants, between October 2018 and May 2019. Further clinical data were extracted from medical records. Samples were screened by molecular and serological tests. Out of 780 participants, 93.1% (95%CI: 91.1–94.7%) presented previous DENV exposure (IgG). ZIKV, CHIKV, and/o...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research