Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke

Early revascularization -the gold standard therapy for ischemic stroke-is often withheld in the elderly population due to high risk of complications. Thus, safe and effective preventive and therapeutic options are needed. The plant-derived omega-3-fatty-acid alpha-linolenic-acid (ALA) has emerged as a potential cardiovascular-protective agent. As of yet, little is known about its potential therapeutic effects on stroke. We hereby aimed to investigate the impact of a clinically relevant long-term dietary intervention with ALA on stroke outcome.

Source: Atherosclerosis - April 19, 2021 Category: Cardiology Authors: Nicole R. Bonetti, Luca Liberale, Alexander Akhmedov, Lisa Pasterk, Sara Gobbato, Yustina M. Puspitasari, Ana Vukolic, Seyed Soheil Saeedi Saravi, Bernd Coester, Carla Horvath, Elena Osto, Fabrizio Montecucco, Thomas F. L üscher, Jürg H. Beer, Giovanni Source Type: research