Investigation of oral malodor prevention by dentifrices as measured by VSC reduction

The oral malodor reduction efficacy of dentifrices containing stannous fluoride (SnF 2 ) or zinc plus arginine (Zn/Arg) was evaluated using a halimeter to measure volatile sulfur compounds (VSCs) in two randomized, controlled, single-blind, cross-over pilot clinical trials. Study 1 ( N = 16) had five 1100 ppm F dentifrices and five treatment periods: negative control (NC): 0.243% sodium fluoride (NaF); SnF 2 A: 0.454% SnF 2 + pyrophosphate; SnF 2 B: 0.454% SnF 2 + sodium hexametaphosphate; SnF 2 C: 0.454% SnF 2 + citrate; and SnF 2 D: experimental 0.454% SnF 2 with increased bioavailable Sn. Study 2 ( N = 16) had four 1450 ppm F dentifrices and four treatment periods: NC: 0.1% NaF + 0.76% sodium monofluorophosphate; Zn/Arg: NaF + zinc + arginine; SnF 2 E: 0.454% SnF 2 + 0.078% NaF + sodium hexametaphosphate; SnF 2 F: 0.454% SnF 2 + 0.078% N...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Source Type: research