TNM 8 staging is a better prognosticator than TNM 7 for patients with locally advanced oral cavity squamous cell carcinoma treated with surgery and post-operative radiotherapy

Oral cavity squamous cell carcinoma (OCSCC) is a challenging disease to manage, with recurrence rates higher than for other head and neck cancers (1, 2). Locally advanced OCSCC is conventionally treated by primary surgery and post-operative radiotherapy (PORT) with the addition of concurrent chemotherapy for high risk cases. However, despite this multi-modality approach, the 5 year survival rate is only ∼ 50% (3). Locoregional recurrence is common, (4) with limited salvage treatments available and survival after disease recurrence is extremely poor,

Source: Radiotherapy and Oncology - April 9, 2021 Category: Radiology Authors: K. Sambasivan, I. Sassoon, S. Thavaraj, R. Kennedy, G. Doss, A. Michaelidou, E. Odell, A. Sandison, G. Hall, P. Morgan, L.H.C. Collins, A. Lyons, L. Cascarini, A. Fry, R. Oakley, R. Simo, J.P. Jeannon, I. Petkar, M. Reis Ferreira, A.Kong, M. Lei, T. Guer Tags: Original Article Source Type: research