LINGO-1 shRNA protects the brain against ischemia/reperfusion injury by inhibiting the activation of NF- κB and JAK2/STAT3

In conclusion, our data suggest that shLINGO-1 attenuated ischemic injury by negatively regulating NF-KB and JAK2/STAT3 pathways, highlighting a novel therapeutic target for ischemic stroke.
Source: Human Cell - Category: Cytology Source Type: research