BIIB093 (intravenous glibenclamide) for the prevention of severe cerebral edema

CONCLUSION: Studies analyzing the GAMES-Pilot and GAMES-PR trials suggest that glibenclamide has a moderate, however, measurable effect on intermediate biomarkers and clinical endpoints. Meaningful conclusions are limited by the small sample size of patients studied.PMID:33767884 | PMC:PMC7982107 | DOI:10.25259/SNI_933_2020

Source: Surgical Neurology International - March 26, 2021 Category: Neurosurgery Authors: Daniel W Griepp Jason Lee Christina M Moawad Cyrus Davati Juliana Runnels Brian Fiani Source Type: research