Hypertrophic Cardiomyopathy: A Species-Spanning Pathology

Hypertrophic cardiomyopathy (HCM), a leading cause of sudden death among athletes and young adults is not uniquely human.1 The disorder has been diagnosed in a wide range of other mammalian species and is seen with some frequency in certain domestic animals (Figure 1). 2-16 The clinical characteristics, natural history and therapeutic interventions are similar across species. Comparative genomic analyses point to overlapping genetic basis for the disorder in humans and other animals, in particular certain domestic cat breeds.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research