Thioredoxin deficiency exacerbates vascular dysfunction during diet ‐induced obesity in small mesenteric artery in mice

ConclusionsOur results indicate that deficiency of active Trx exacerbates MA contractile and relaxing properties during diet ‐induced obesity demonstrating that loss of redox balance in obesity is a key mechanism of vascular endothelial dysfunction.

Source: Microcirculation - December 30, 2020 Category: Research Authors: Shannon Dunn, Robert H. Hilgers, Kumuda C. Das Tags: ORIGINAL ARTICLE Source Type: research